PARTICIPANTS
Back
Medema, René
The Medema group has been studying cell cycle checkpoints for several years, with particular emphasis on mitotic checkpoints. The main goal is to understand the mechanisms that ensure chromosome stability in healthy cells, and how this quality control mechanism is altered in cancer. The newly acquired insights should help us understand if we can take advantage of this defect in cancer cells to develop novel anti-cancer strategies. The main lines of research in the laboratory are:
• checkpoint recovery
• spindle assembly
• transcriptional regulation in G2